Seattle (23-19) will be trying to take the series lead when they visit Petco Park on Friday night to face San Diego (27-15) in the first game of their three-game interleague series at 9:40 PM. ET. Read on to find out which team picks up the win in this Mariners vs. Padres prediction, and try our MLB Betting Picks. Logan Evans, 1-1, 6.60 ERA, will get the start for the Mariners. The Padres will counter with Stephen Kolek, 2-0, 0.00 ERA. Seattle is 7-3 in its last 10 games against San Diego.  ... Read more

On Friday evening, the Seattle Mariners (23-19, 1st in AL West) travel to San Diego, CA, to take on the Padres (27-15, 2nd in NL West) in the first game of their three-game set at Petco Park, and we have you covered with our Padres versus Mariners prediction. The Padres will send RHP Stephen Kolek (2-0, 0.00 ERA) to the mound for his second start of the season. The Mariners have not named their starting pitchers for the upcoming series as of the publication of this article, but the most likely c... Read more

Get our free Baseball betting pick for the San Diego Padres vs Seattle Mariners matchup and gain an edge as a Baseball bettor. Read more

The Padres are -155 favorites vs the Mariners Mariners vs Padres Over / Under today: 8.5 Runs Mariners / Padres TV Channel: ATV The Seattle Mariners (+130) visit Petco Park to take on the San Diego Padres (-155) on Friday, May 16, 2025. First pitch is scheduled for 9:40pm EDT in San Diego, CA, CA. This season, the Mariners are 23-19 against the spread (ATS), while the Padres are 26-16 ATS. Mariners vs Padres Starting Pitchers Today: Mariners starting pitcher: Logan Evans 1-1, 6.61 ERA Padres sta... Read more

San Diego Padres (27-15) vs Seattle Mariners (23-19) Game Info: Friday, May 16, 2025 at 9:40 pm (Petco Park) L. Evans (R) vs S. Kolek (R) Betting Odds: San Diego Padres -155 / Seattle Mariners +130 --- Over/Under: 8.5 Click Here for the Latest Odds Where to Watch: Apple TV+ In this article, we will formulate a Mariners vs Padres prediction for this MLB game on Friday, May 16, at PETCO Park in San Diego, California. Let’s take a look at the prediction for this MLB matchup. Seattle Mariners Bettin... Read more