On Friday night, the San Diego Padres will play the Pittsburgh Pirates at PNC Park, and we have you ready to go with our Padres vs. Pirates prediction. First pitch from Pittsburgh is at 6:40 p.m. ET. San Diego and Pittsburgh met six times last season. The Friars swept the season series and are 7-3 in their last ten meetings with the Buccos. The total was split 5-5 in those ten games. If you want the Padres vs. Pirates prediction, read on and check out our MLB Predictions to beat the sportsbooks!... Read more

In our Padres vs. Pirates prediction, the San Diego Padres are second in the NL West with a 19-11 record so far. They are having right-hander Dylan Cease get the start as he is coming off a loss against the Tampa Bay Rays where he threw 4.1 innings and gave up three runs (two earned) on six hits with four walks and six strikeouts.    The Pittsburgh Pirates are struggling as they are sitting in fifth place in the NL Central with a 12-20 record entering this game. Righty Mitch Keller takes th... Read more

Get our free Baseball betting pick for the Pittsburgh Pirates vs San Diego Padres matchup and gain an edge as a Baseball bettor. Read more

Pittsburgh Pirates (12-20) vs San Diego Padres (19-11) Game Info: Friday, May 2, 2025 at 6:40 pm (PNC Park) D. Cease (R) vs M. Keller (R) Betting Odds: Pittsburgh Pirates +130 / San Diego Padres -155 --- Over/Under: 8 Click Here for the Latest Odds Where to Watch: Apple TV+ The San Diego Padres are visiting the Pittsburgh Pirates on Friday, May 2nd at the PNC Park in the opening game of this series. We will look at this from a betting perspective and determine the best bets for this game. Here’s... Read more